An Approach to Binary Classification of Alzheimer’s Disease Using LSTM

Author:

Salehi Waleed1ORCID,Baglat Preety2,Gupta Gaurav1ORCID,Khan Surbhi Bhatia3ORCID,Almusharraf Ahlam4ORCID,Alqahtani Ali5ORCID,Kumar Adarsh67ORCID

Affiliation:

1. Yogananda School of AI, Shoolini University, Bajhol 173229, India

2. Interactive Technologies Institute (ITI/LARSyS and ARDITI), University of Madeira, 9000-082 Funchal, Portugal

3. Department of Data Science, School of Science, Engineering and Environment, University of Salford, Manchester M5 4WT, UK

4. Department of Business Administration, College of Business and Administration, Princess Nourah Bint Abdulrahman University, P.O. Box 84428, Riyadh 11671, Saudi Arabia

5. Department of Networks and Communications Engineering, College of Computer Science and Information Systems, Najran University, Najran 61441, Saudi Arabia

6. School of Computer Science, Mohammed VI Polytechnic University, Ben Guerir 43150, Morocco

7. School of Computer Science, University of Petroleum and Energy Studies, Dehradun 248007, India

Abstract

In this study, we use LSTM (Long-Short-Term-Memory) networks to evaluate Magnetic Resonance Imaging (MRI) data to overcome the shortcomings of conventional Alzheimer’s disease (AD) detection techniques. Our method offers greater reliability and accuracy in predicting the possibility of AD, in contrast to cognitive testing and brain structure analyses. We used an MRI dataset that we downloaded from the Kaggle source to train our LSTM network. Utilizing the temporal memory characteristics of LSTMs, the network was created to efficiently capture and evaluate the sequential patterns inherent in MRI scans. Our model scored a remarkable AUC of 0.97 and an accuracy of 98.62%. During the training process, we used Stratified Shuffle-Split Cross Validation to make sure that our findings were reliable and generalizable. Our study adds significantly to the body of knowledge by demonstrating the potential of LSTM networks in the specific field of AD prediction and extending the variety of methods investigated for image classification in AD research. We have also designed a user-friendly Web-based application to help with the accessibility of our developed model, bridging the gap between research and actual deployment.

Funder

Princess Nourah Bint Abdulrahman University, Riyadh, Saudi Arabia

Publisher

MDPI AG

Subject

Bioengineering

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