Author:
Belyaeva Kseniya V.,Nikitina Lina P.,Gen’ Veronika S.,Tomilin Denis N.,Sobenina Lyubov N.,Afonin Andrei V.,Oparina Ludmila A.,Trofimov Boris A.
Abstract
Acylethynylpyrroles, now readily available by the cross-coupling of pyrroles with acylbromoacetylenes in solid Al2O3 media, in the presence of 1-methylimidazole underwent unprecedentedly easy (40–45 °C) cyclodimerization into bis(acylmethylidene)dipyrrolo[1,2-a:1′,2′-d]pyrazines in up to 51% yield. Some other organic and inorganic basic catalysts can also trigger this cyclodimerization, but less efficiently.
Funder
Russian Science Foundation
Subject
Physical and Theoretical Chemistry,Catalysis,General Environmental Science
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