Acylmethylidenepyrrolo[1,2-<i>c</i>]oxazoles <i>via</i> [3+2]-cyclization of 2-acylethynylpyrroles with carbonyl compounds-Reference-Cited by-同舟云学术

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Acylmethylidenepyrrolo[1,2-c]oxazoles via [3+2]-cyclization of 2-acylethynylpyrroles with carbonyl compounds

Published:2023 Issue:38 Volume:47 Page:17810-17816
ISSN:1144-0546
Container-title:New Journal of Chemistry
language:en
Short-container-title:New J. Chem.

Author:

Tomilin Denis N.¹,Stepanova Sophia A.¹,Sobenina Lyubov N.¹,Ushakov Igor A.¹,Trofimov Boris A.¹^ORCID

Affiliation:

1. A.E. Favorsky Irkutsk Institute of Chemistry, Siberian Branch, Russian Academy of Science, 1 Favorsky Str, Irkutsk 664033, Russia

Abstract

Acylethynylpyrroles, readily available from acylbromoacetylenes and pyrroles, smoothly undergo [3+2]-cyclization with ketones and aldehydes (room temperature) to give acylmethylidenepyrrolo[1,2-c]oxazoles.

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,General Chemistry,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2023/NJ/D3NJ03142J

Reference30 articles.

1. Recent progress in the total synthesis of pyrrole-containing natural products (2011–2020)

2. Bioactive pyrrole-based compounds with target selectivity

3. Synthesis Strategies and Medicinal Value of Pyrrole and its Fused Heterocyclic Compounds

4. Recent synthetic journey on pyrrole-fused compounds

5. Recent advance in oxazole-based medicinal chemistry

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