A Review of In-Vivo and In-Vitro Real-Time Corrosion Monitoring Systems of Biodegradable Metal Implants

Abstract

In current modern medicine, biodegradable metal implants are still considered a work-in-progress between the collaborations of both scientists and engineers. As of now, one of the obstacles to this development is monitoring the corrosion rate of the implant. When a biodegradable metal implant (made of Mg, Zn, etc.) is introduced into the harsh environment of the human body, corrosion naturally occurs, causing metal ions to be released which may result in undesired health effects. The released products of the corroding implant can be used to monitor the implant condition. This paper discusses the current real-time corrosion monitoring systems (i.e., electrochemical-, microsensor-, and microdialysis-based) in-vivo and in-vitro. It is acknowledged that the progress in this sector still requires extensive research in order to obtain a desirable monitoring system and it is hoped that this review paper contributes to the research.