A New Direction for the Green, Environmentally Friendly and Sustainable Bioproduction of Aminobenzoic Acid and Its Derivatives

Author:

Xiao Shujian1,Zeng Rumei1,Wang Bangxu1,Zhang Suyi23,Cheng Jie123ORCID,Zhang Jiamin1

Affiliation:

1. Meat Processing Key Laboratory of Sichuan Province, College of Food and Biological Engineering, Chengdu University, Chengdu 610106, China

2. Postdoctoral Research Station of Luzhou Laojiao Company, Luzhou Laojiao Co., Ltd., Luzhou 646000, China

3. Solid-State Brewing Technology Innovation Center of Sichuan, Luzhou 646000, China

Abstract

Aminobenzoic acid and its derivatives are a class of aromatic compounds that are important foundational chemicals for various dyes, food additives, and pharmaceuticals. Their production relies on chemical synthesis using petroleum-derived substances such as benzene as precursors, but due to the toxicity, environmental pollution, and non-renewable nature of raw materials in chemical synthesis, some suitable alternative methods are gradually being developed. Green, environmentally friendly, and sustainable biosynthesis methods have gradually been favored by researchers, especially after the discovery of the synthetic pathways of aminobenzoic acid and its derivatives in plants and microorganisms. Based on the purpose of protecting the ecological environment, reducing the use of non-renewable resources, and providing theoretical support for industrial green development, this article reviews the biosynthesis pathways of ortho-aminobenzoic acid, meta-aminobenzoic acid, para-aminobenzoic acid, and its derivatives such as catechol, folic acid, etc., and lists some examples of biosynthesis, analyzes their advantages and disadvantages, summarizes and looks forward to the future development direction of biosynthesis of aminobenzoic acid and its derivatives.

Funder

the earmarked fund

National Modern Agricultural Industrial Technology System, Sichuan Innovation Team Construction Project

Open Funding Project of Meat Processing Key Laboratory of Sichuan Province

Solid-state Brewing Technology Innovation Center of Sichuan

Publisher

MDPI AG

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