Dual-Source Photon-Counting Computed Tomography—Part I: Clinical Overview of Cardiac CT and Coronary CT Angiography Applications

Author:

Cademartiri Filippo1ORCID,Meloni Antonella12ORCID,Pistoia Laura1,Degiorgi Giulia1,Clemente Alberto1ORCID,Gori Carmelo De1ORCID,Positano Vincenzo12ORCID,Celi Simona3ORCID,Berti Sergio4ORCID,Emdin Michele5,Panetta Daniele6ORCID,Menichetti Luca6ORCID,Punzo Bruna7,Cavaliere Carlo7,Bossone Eduardo8ORCID,Saba Luca9,Cau Riccardo9ORCID,Grutta Ludovico La10,Maffei Erica1

Affiliation:

1. Department of Radiology, Fondazione Monasterio/CNR, 56124 Pisa, Italy

2. Department of Bioengineering, Fondazione Monasterio/CNR, 56124 Pisa, Italy

3. BioCardioLab, Department of Bioengineering, Fondazione Monasterio/CNR, 54100 Massa, Italy

4. Cardiology Unit, Ospedale del Cuore, Fondazione Monasterio/CNR, 54100 Massa, Italy

5. Department of Cardiology, Fondazione Monasterio/CNR, 56124 Pisa, Italy

6. Institute of Clinical Physiology, National Council of Research, 56124 Pisa, Italy

7. Department of Radiology, IRCCS SynLab-SDN, 80131 Naples, Italy

8. Department of Cardiology, Ospedale Cardarelli, 80131 Naples, Italy

9. Department of Radiology, University Hospital, 09042 Monserrato, Italy

10. Department of Radiology, University Hospital “P. Giaccone”, 90127 Palermo, Italy

Abstract

The photon-counting detector (PCD) is a new computed tomography detector technology (photon-counting computed tomography, PCCT) that provides substantial benefits for cardiac and coronary artery imaging. Compared with conventional CT, PCCT has multi-energy capability, increased spatial resolution and soft tissue contrast with near-null electronic noise, reduced radiation exposure, and optimization of the use of contrast agents. This new technology promises to overcome several limitations of traditional cardiac and coronary CT angiography (CCT/CCTA) including reduction in blooming artifacts in heavy calcified coronary plaques or beam-hardening artifacts in patients with coronary stents, and a more precise assessment of the degree of stenosis and plaque characteristic thanks to its better spatial resolution. Another potential application of PCCT is the use of a double-contrast agent to characterize myocardial tissue. In this current overview of the existing PCCT literature, we describe the strengths, limitations, recent applications, and promising developments of employing PCCT technology in CCT.

Publisher

MDPI AG

Subject

General Medicine

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