Abstract
Pesticide exposure has deleterious effects on human health and development; however, no review has been conducted on human exposure to pesticides and the risk of congenital malformations and cancer in the same cohort. We systematically reviewed the evidence for this relationship following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis guidelines. Four databases, namely, PubMed, Scopus, Cochrane Library, and BVS, were searched for studies deposited till July 2020 that examined the influence of pesticide exposure on congenital malformations and cancer outcomes in the same cohort. Seven studies were systematically included in this review. Among these, four were case–control studies, two were cross-sectional studies, and one was a longitudinal cohort study. The sources of contamination were food, water, or exposure during agricultural work. A link between the occurrence of cancer, congenital malformations, and exposure to pesticides was observed in most studies.
Subject
Chemical Health and Safety,Health, Toxicology and Mutagenesis,Toxicology
Reference80 articles.
1. Chemical pesticides and human health: The urgent need for a new concept in agriculture;Nicolopoulou-Stamati;Front. Public Health,2016
2. Lopes-Ferreira, M., Maleski, A.L.A., Balan-Lima, L., Bernardo, J.T.G., Hipolito, L.M., Seni-Silva, A.C., Batista-Filho, J., Falcao, M.A.P., and Lima, C. Impact of pesticides on human health in the last six years in Brazil. Int. J. Environ. Res. Public Health, 2022. 19.
3. How much global ill health is attributable to environmental factors?;Smith;Epidemiology,1999
4. Preventing Disease through Healthy Environments: A Global Assessment of the Burden of Disease from Environmental Risks. 2022.
5. Guo, W., Pan, B., Sakkiah, S., Yavas, G., Ge, W., Zou, W., Tong, W., and Hong, H. Persistent organic pollutants in food: Contamination sources, health effects and detection methods. Int. J. Environ. Res. Public Health, 2019. 16.
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