Abstract
Tularemia is a severe infectious disease caused by the Gram-negative bacteria Francisella tularensis. F. tularensis is currently divided into three subspecies, holarctica, tularensis, and mediasiatica, which differ in their virulence and geographic distribution. Subspecies mediasiatica is the least studied because of its very low documented virulence for humans and limited geographic distribution. It was discovered in sparsely populated regions of Central Asia. Since 2011, a new subsp. mediasiatica lineage was identified in Altai (Russia). In 2021, we isolated one subsp. mediasiatica strain in Krasnoyarsk Territory. In spite of its geographic origin, 500 km east from Altai, this strain belongs to the Altai lineage and contributes surprisingly little genetic diversity to previous knowledge.
Funder
Sectoral Scientific Program of the Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing
Reference16 articles.
1. Ecology of Francisella tularensis;Telford;Annu. Rev. Entomol.,2020
2. Evolution of subspecies of Francisella tularensis;Svensson;J. Bacteriol.,2005
3. Comparative review of Francisella tularensis and Francisella novicida;Kingry;Front. Cell. Infect. Microbiol.,2014
4. Timofeev, V., Bakhteeva, I., Titareva, G., Kopylov, P., Christiany, D., Mokrievich, A., Dyatlov, I., and Vergnaud, G. Russian isolates enlarge the known geographic diversity of Francisella tularensis subsp. mediasiatica. PLoS ONE, 2017. 12.
5. Worldwide genetic relationships among Francisella tularensis isolates determined by multiple-locus variable-number tandem repeat analysis;Johansson;J. Bacteriol.,2004
Cited by
2 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献