Abstract
Children and adults with single ventricle congenital heart disease (CHD) develop many sequelae during staged surgical palliation. Universal pulmonary vascular sequelae in this patient population include two inter-related but distinct complications: pulmonary arteriovenous malformations (PAVMs) and aortopulmonary collaterals (APCs). This review highlights what is known and unknown about these vascular sequelae focusing on diagnostic testing, pathophysiology, and areas in need of further research.
Funder
National Heart Lung and Blood Institute
National Center for Advancing Translational Sciences
Additional Ventures
Subject
Pharmacology (medical),General Pharmacology, Toxicology and Pharmaceutics