Management of the Sickle Cell Trait: An Opinion by Expert Panel Members-Reference-Cited by-同舟云学术

Management of the Sickle Cell Trait: An Opinion by Expert Panel Members

Published:2023-05-12 Issue:10 Volume:12 Page:3441
ISSN:2077-0383
Container-title:Journal of Clinical Medicine
language:en
Short-container-title:JCM

Author:

Pinto Valeria Maria¹^ORCID,De Franceschi Lucia²^ORCID,Gianesin Barbara¹³,Gigante Antonia³⁴,Graziadei Giovanna⁵^ORCID,Lombardini Letizia⁶,Palazzi Giovanni⁷,Quota Alessandra⁸,Russo Rodolfo⁹,Sainati Laura¹⁰,Venturelli Donatella¹¹,Forni Gian Luca¹^ORCID,Origa Raffaella¹²^ORCID

Affiliation:

1. Centro della Microcitemia, Anemie Congenite e Dismetabolismo del Ferro, E.O. Ospedali Galliera, 16128 Genova, Italy

2. Dipartimento di Medicina AOUI, Università di Verona, 37124 Verona, Italy

3. ForAnemia Foundation, 16124 Genova, Italy

4. Società Italiana Talassemie ed Emoglobinopatie (SITE), 09100 Cagliari, Italy

5. Centro Malattie Rare Internistiche, Medicina Generale, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico, 20122 Milano, Italy

6. Centro Nazionale Trapianti, Istituto Superiore di Sanità, 00161 Roma, Italy

7. U.O. Oncoematologia Pediatrica, Azienda Ospedaliero-Universitaria di Modena, 41125 Modena, Italy

8. UOSD Talassemia, P.O. Vittorio Emanuele, 93012 Gela, Italy

9. Clinica Nefrologica, Dialisi e Trapianto, Dipartimento di Medicina Integrata con il Territorio, IRCCS Ospedale Policlinico San Martino, 16132 Genova, Italy

10. Oncoematologia Pediatrica, Azienda Ospedaliera-Università di Padova, 35128 Padova, Italy

11. Servizio Immunotrasfusionale, Azienda Ospedaliero-Universitaria di Modena, 41125 Modena, Italy

12. Talassemia, Ospedale Pediatrico Microcitemico ‘A.Cao’, ASL8, Università di Cagliari, 09121 Cagliari, Italy

Abstract

The number of individuals with the sickle cell trait exceeds 300 million worldwide, making sickle cell disease one of the most common monogenetic diseases globally. Because of the high frequency of sickle cell disease, reproductive counseling is of crucial importance. In addition, unlike other carrier states, Sickle Cell Trait (SCT) seems to be a risk factor for several clinical complications, such as extreme exertional injury, chronic kidney disease, and complications during pregnancy and surgery. This expert panel believes that increasing knowledge about these clinical manifestations and their prevention and management can be a useful tool for all healthcare providers involved in this issue.

Publisher

MDPI AG

Subject

General Medicine

Link

https://www.mdpi.com/2077-0383/12/10/3441/pdf

Reference167 articles.

1. Sickle Cell Disease;Ware;Lancet,2017

2. Sickle-Cell Disease;Rees;Lancet,2010

3. Dietary -3 Fatty Acids Protect against Vasculopathy in a Transgenic Mouse Model of Sickle Cell Disease;Kalish;Haematologica,2015

4. Formation of Dense Erythrocytes in SAD Mice Exposed to Chronic Hypoxia: Evaluation of Different Therapeutic Regimens and of a Combination of Oral Clotrimazole and Magnesium Therapies;Brugnara;Blood,1999

5. Ca2+-Activated K+ Channels of Human and Rabbit Erythrocytes Display Distinctive Patterns of Inhibition by Venom Peptide Toxins;Brugnara;J. Membr. Biol.,1995

Cited by 6 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A moonlighting job for α-globin in blood vessels;Blood;2024-08-22

2. Screening for sickle cell disease: focus on newborn investigations;Clinical Chemistry and Laboratory Medicine (CCLM);2024-06-19

3. Sickle Cell Screening in Adults: A Current Review of Point-of-Care Testing;Journal of Hematology;2024-06

4. Genome-Wide Analysis of Exertional Rhabdomyolysis in Sickle Cell Trait Positive African Americans;Genes;2024-03-26

5. Genetic Information to Share with Parents when Newborn Screening Reveals the Presence of Sickle Cell Trait;International Journal of Pediatrics;2024-02-22