The Role of Gluten in Gastrointestinal Disorders: A Review

Author:

Cenni Sabrina1,Sesenna Veronica2,Boiardi Giulia2,Casertano Marianna3,Russo Giuseppina3,Reginelli Alfonso4,Esposito Susanna2,Strisciuglio Caterina3

Affiliation:

1. Department of Experimental Medicine, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy

2. Department of Medicine and Surgery, Pediatric Clinic, University of Parma, 43126 Parma, Italy

3. Department of Woman, Child and General and Specialist Surgery, University of Campania “Luigi Vanvitelli”, 80138 Naples, Italy

4. Radiology Unit, Department of Precision Medicine, University of Campania “L. Vanvitelli”, 80138 Napoli, Italy

Abstract

Gluten is only partially digested by intestinal enzymes and can generate peptides that can alter intestinal permeability, facilitating bacterial translocation, thus affecting the immune system. Few studies addressed the role of diet with gluten in the development of intestinal inflammation and in other gastrointestinal disorders. The aim of this narrative review was to analyse the role of gluten in several gastrointestinal diseases so as to give a useful overview of its effectiveness in the prevention and management of these disorders.

Publisher

MDPI AG

Subject

Food Science,Nutrition and Dietetics

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