Imaging of Strictures in Crohn’s Disease

Author:

Minordi Laura Maria1ORCID,Larosa Luigi1ORCID,Bevere Antonio2ORCID,D’Angelo Francesca Bice2,Pierro Antonio3,Cilla Savino4ORCID,Del Ciello Annemilia1ORCID,Scaldaferri Franco5ORCID,Barbaro Brunella12

Affiliation:

1. Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Roma, Italy

2. Università Cattolica del Sacro Cuore, L.go F. Vito 1, 00168 Rome, Italy

3. Radiology Unit, San Timoteo Hospital, 86039 Termoli, Italy

4. Medical Physics Unit, Responsible Research Hospital, 86100 Campobasso, Italy

5. CEMAD Digestive Diseases Center, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy

Abstract

Crohn’s disease (CD) is a chronic inflammation of the digestive tract, and it frequently affects young patients. It can involve any intestinal segment, even though it frequently affects the distal ileum. Up to 80% of patients with CD present with inflammatory behavior, and 5% to 28% develop stricturing disease. Based on the predominant mechanism causing them, strictures can be categorized as inflammatory, fibrotic, or mixed. Determining the relative amounts of inflammation and fibrosis in a stricture can influence treatment decisions. Imaging is an extremely useful tool in patients with small bowel stricturing CD to confirm the diagnosis and to evaluate disease characteristics, usually using CT or MRI. The aim of this paper is to describe how imaging can evaluate a patient with small bowel CD stricture.

Publisher

MDPI AG

Subject

Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics

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