Agarose Gel Characterization for the Fabrication of Brain Tissue Phantoms for Infrared Multispectral Vision Systems

Author:

Albor-Ramírez Efraín1ORCID,Reyes-Alberto Miguel1ORCID,Vidal-Flores Luis M.1ORCID,Gutierrez-Herrera Enoch1,Padilla-Castañeda Miguel A.1ORCID

Affiliation:

1. Applied Sciences and Technology Institute ICAT, National Autonomous University of Mexico UNAM, Ciudad Universitaria, Mexico City 04510, Mexico

Abstract

Synthetic phantoms that recreate the characteristics of biological tissues are valuable tools for systematically studying and comprehending physiologies, pathologies, and biological processes related to tissues. The reproduction of mechanical and optical properties allows for the development and evaluation of novel systems and applications in areas such as imaging, optics, ultrasound, or dosimetry, among others. This paper proposes a methodology for manufacturing agarose-based phantoms that mimics the optical properties of healthy brain tissue within the wavelength infrared range of 800 to 820 nm. The fabrication of such phantoms enables the possibility of testing and experimentation in controlled and safe environments toward the design of new near-infrared multispectral imaging systems in neurosurgery. The results of an experimental optical characterization study indicate the validity and reliability of the proposed method for fabricating brain tissue phantoms in a cost-effective and straightforward fashion.

Funder

Laboratorio de Investigación y Desarrollo de Simuladores Clínicos y Cirugía Asistida por Computadora

Metodología de realidad aumentada multiespectral para la identificación y localización de tejido patológico en intervenciones quirúrgicas guiadas por computadora, CONAHCYT

Esquema de neuro navegación quirúrgica por imágenes multiespectrales y simulación biomecánica para resección de tumores cerebrales guiada por computadora

Publisher

MDPI AG

Subject

Polymers and Plastics,Organic Chemistry,Biomaterials,Bioengineering

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