Advances in the Metabolic Mechanism and Functional Characteristics of Equol

Author:

Gong Yining12,Lv Jiaping2,Pang Xiaoyang2ORCID,Zhang Shuwen2,Zhang Guofang1ORCID,Liu Libo1,Wang Yunna2,Li Chun13ORCID

Affiliation:

1. Key Laboratory of Dairy Sciences, Ministry of Education, College of Food Science, Northeast Agricultural University, Harbin 150030, China

2. Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences, No. 2 Yuan Ming Yuan West Road, Beijing 100193, China

3. Heilongjiang Green Food Science Research Institute, Harbin 150030, China

Abstract

Equol is the most potent soy isoflavone metabolite and is produced by specific intestinal microorganisms of mammals. It has promising application possibilities for preventing chronic diseases such as cardiovascular disease, breast cancer, and prostate cancer due to its high antioxidant activity and hormone-like activity. Thus, it is of great significance to systematically study the efficient preparation method of equol and its functional activity. This paper elaborates on the metabolic mechanism of equol in humans; focuses on the biological characteristics, synthesis methods, and the currently isolated equol-producing bacteria; and looks forward to its future development and application direction, aiming to provide guidance for the application and promotion of equol in the field of food and health products.

Funder

Agricultural Science and Technology Innovation Program of Institute of Food Science and Technology, Chinese Academy of Agricultural Sciences

National Natural Science Foundation of China

China Agriculture Research System-National Dairy Industry and Technology System

Publisher

MDPI AG

Subject

Plant Science,Health Professions (miscellaneous),Health (social science),Microbiology,Food Science

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