Baculovirus Display of Peptides and Proteins for Medical Applications-Reference-Cited by-同舟云学术

Baculovirus Display of Peptides and Proteins for Medical Applications

Published:2023-02-01 Issue:2 Volume:15 Page:411
ISSN:1999-4915
Container-title:Viruses
language:en
Short-container-title:Viruses

Author:

Rodríguez-Hernández Aaron Pavel¹,Martínez-Flores Daniel¹^ORCID,Cruz-Reséndiz Adolfo²,Padilla-Flores Teresa¹,González-Flores Rodrigo¹^ORCID,Estrada Kenia¹^ORCID,Sampieri Alicia¹,Camacho-Zarco Aldo Román³,Vaca Luis¹^ORCID

Affiliation:

1. Instituto de Fisiología Celular, Universidad Nacional Autónoma de México, Ciudad Universitaria, Mexico City 04510, Mexico

2. Departamento de Microbiología y Parasitología, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria, Mexico City 04510, Mexico

3. European Molecular Biology Laboratory, Grenoble Outstation, EMBL Grenoble, CEDEX 9, 38042 Grenoble, France

Abstract

Baculoviridae is a large family of arthropod-infective viruses. Recombinant baculoviruses have many applications, the best known is as a system for large scale protein production in combination with insect cell cultures. More recently recombinant baculoviruses have been utilized for the display of proteins of interest with applications in medicine. In the present review we analyze the different strategies for the display of proteins and peptides on the surface of recombinant baculoviruses and provide some examples of the different proteins displayed. We analyze briefly the commercially available systems for recombinant baculovirus production and display and discuss the future of this emerging and powerful technology.

Funder

Dirección General de Asuntos del Personal Académico

Publisher

MDPI AG

Subject

Virology,Infectious Diseases

Link

https://www.mdpi.com/1999-4915/15/2/411/pdf

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