Impact of COVID-19 on the Care of Patients with HIV Infection

Author:

Rosas Cancio-Suárez Marta12ORCID,Alonso Cecilia1,Vivancos María12,Pérez-Elías María12,Cárdenas María3,Vélez-Díaz-Pallarés Manuel4ORCID,Corbacho María1,Martín-Pedraza Laura12,Muriel Alfonso56,Martínez-Sanz Javier12,Moreno Santiago126ORCID

Affiliation:

1. Department of Infectious Diseases, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Carretera de Colmenar Km 9.1, 28034 Madrid, Spain

2. CIBERINFEC, 28029 Madrid, Spain

3. Microbiology Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Carretera de Colmenar Km 9.1, 28034 Madrid, Spain

4. Pharmacy Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, Carretera de Colmenar Km 9.1, 28034 Madrid, Spain

5. Biostatistics Department, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigación Sanitaria IRYCIS, 28034 Madrid, Spain

6. Department of Medicine, University of Alcalá de Henares, Guadalajara Campus, 28801 Alcalá de Henares, Spain

Abstract

The COVID-19 pandemic and associated lockdown measures have been associated with substantial disruptions to health care services, including screening for human immunodeficiency virus (HIV) and management of people living with HIV (PLWH). Data from 3265 patients were examined in a retrospective cohort study. We compared outpatient follow-up for PLWH, the number of new patients, treatment adherence, hospitalizations, and deaths during the “pandemic period” (March 2020 to February 2021), the “pre-pandemic period” (the equivalent time frame in 2019), and the “post-pandemic period” (March to September 2021). During the pandemic period, the number of new patients seen at the HIV clinic (116) as well as the requested viral load tests (2414) decreased significantly compared to the pre-pandemic (204 and 2831, respectively) and post-pandemic periods (146 and 2640, respectively) (p < 0.01 for all the comparisons). However, across the three study periods, the number of drug refills (1385, 1330, and 1411, respectively), the number of patients with undetectable viral loads (85%, 90%, and 93%, respectively), and the number of hospital admissions among PLWH remained constant. Despite the COVID-19 pandemic’s impact, our findings show stability in the retention of clinical care, adherence to treatment, and viral suppression of PLWH, with no significant impact on hospitalization rates or all-cause mortality.

Funder

Instituto de Salud Carlos III

European Union

Publisher

MDPI AG

Subject

General Medicine

Reference26 articles.

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3. Guidelines for Improving Entry Into and Retention in Care and Antiretroviral Adherence for Persons With HIV: Evidence-Based Recommendations From an International Association of Physicians in AIDS Care Panel;Thompson;Ann. Intern. Med.,2012

4. (2022, August 08). Royal Decree 463/2020, of March 14, Declaring the State of Alarm for the Management of the Health Crisis Situation Caused by COVID-19. Available online: https://www.boe.es/eli/es/rd/2020/03/14/463.

5. Preparing for and responding to COVID-19′s ‘second hit’;Nundy;Healthcare,2020

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