Machine Learning for Postoperative Continuous Recovery Scores of Oncology Patients in Perioperative Care with Data from Wearables

Author:

van den Eijnden Meike A. C.12,van der Stam Jonna A.23ORCID,Bouwman R. Arthur45ORCID,Mestrom Eveline H. J.4,Verhaegh Wim F. J.1ORCID,van Riel Natal A. W.2ORCID,Cox Lieke G. E.1

Affiliation:

1. Philips Research, 5656 AE Eindhoven, The Netherlands

2. Department Biomedical Engineering, Eindhoven University of Technology, 5612 AE Eindhoven, The Netherlands

3. Department of Clinical Chemistry, Catharina Hospital, 5602 ZA Eindhoven, The Netherlands

4. Department of Anaesthesiology, Catharina Hospital, 5602 ZA Eindhoven, The Netherlands

5. Department of Electrical Engineering, Eindhoven University of Technology, 5612 AE Eindhoven, The Netherlands

Abstract

Assessing post-operative recovery is a significant component of perioperative care, since this assessment might facilitate detecting complications and determining an appropriate discharge date. However, recovery is difficult to assess and challenging to predict, as no universally accepted definition exists. Current solutions often contain a high level of subjectivity, measure recovery only at one moment in time, and only investigate recovery until the discharge moment. For these reasons, this research aims to create a model that predicts continuous recovery scores in perioperative care in the hospital and at home for objective decision making. This regression model utilized vital signs and activity metrics measured using wearable sensors and the XGBoost algorithm for training. The proposed model described continuous recovery profiles, obtained a high predictive performance, and provided outcomes that are interpretable due to the low number of features in the final model. Moreover, activity features, the circadian rhythm of the heart, and heart rate recovery showed the highest feature importance in the recovery model. Patients could be identified with fast and slow recovery trajectories by comparing patient-specific predicted profiles to the average fast- and slow-recovering populations. This identification may facilitate determining appropriate discharge dates, detecting complications, preventing readmission, and planning physical therapy. Hence, the model can provide an automatic and objective decision support tool.

Funder

Rijksdienst voor Ondernemend Nederland

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Biochemistry,Instrumentation,Atomic and Molecular Physics, and Optics,Analytical Chemistry

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