Involvement of Vitamin D3 in the Aging Process According to Sex

Author:

Trifan Daniela Florina1,Tirla Adrian Gheorghe2,Mos Calin2,Danciu Adrian1,Bodog Florian2,Manole Felicia2,Ghitea Timea Claudia3ORCID

Affiliation:

1. Doctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, Romania

2. Faculty of Medicine and Pharmacy, Medicine Department, University of Oradea, 410068 Oradea, Romania

3. Faculty of Medicine and Pharmacy, Department of Pharmacy, University of Oradea, 10, 410068 Oradea, Romania

Abstract

Background/Aim: Rapid onset of facial ptosis can impact physical appearance and compromise the outcomes of facelift procedures. The level of vitamin D has a potential correlation with collagen formation and its deficiency with inflammatory processes that affect the breakdown of hyaluronic acid. This study aims to investigate the potential relationship between accentuated facial ptosis in women and low levels of vitamin D. Furthermore, it aims to explore preventive measures or strategies to slow down facial ptosis and enhance the longevity of facelift results. Materials and Methods: The study was focused on monitoring the vitamin D levels in women and men with advanced facial ptosis and comparing them with a control group. Results: Notably, a direct association between gender and serum vitamin D levels was observed, indicating less sustainable outcomes in women. Conclusions: Women face additional challenges in the aging process due to hormonal shifts after menopause or premenopausal, which are associated with osteoporosis and lower vitamin D levels.

Funder

University of Oradea

Publisher

MDPI AG

Subject

Dermatology,Pharmaceutical Science,Aging,Chemical Engineering (miscellaneous),Surgery

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