Modeling and Simulation of a TFET-Based Label-Free Biosensor with Enhanced Sensitivity

Author:

Choudhury Sagarika1,Baishnab Krishna Lal1,Guha Koushik1ORCID,Jakšić Zoran2ORCID,Jakšić Olga2ORCID,Iannacci Jacopo3ORCID

Affiliation:

1. Department of Electronics and Communication Engineering, National Institute of Technology, Silchar 788010, India

2. Center of Microelectronic Technologies, Institute of Chemistry, Technology and Metallurgy, National Institute of the Republic of Serbia, University of Belgrade, 11000 Belgrade, Serbia

3. Center for Sensors and Devices (SD), Fondazione Bruno Kessler (FBK), 38123 Trento, Italy

Abstract

This study discusses the use of a triple material gate (TMG) junctionless tunnel field-effect transistor (JLTFET) as a biosensor to identify different protein molecules. Among the plethora of existing types of biosensors, FET/TFET-based devices are fully compatible with conventional integrated circuits. JLTFETs are preferred over TFETs and JLFETs because of their ease of fabrication and superior biosensing performance. Biomolecules are trapped by cavities etched across the gates. An analytical mathematical model of a TMG asymmetrical hetero-dielectric JLTFET biosensor is derived here for the first time. The TCAD simulator is used to examine the performance of a dielectrically modulated label-free biosensor. The voltage and current sensitivity of the device and the effects of the cavity size, bioanalyte electric charge, fill factor, and location on the performance of the biosensor are also investigated. The relative current sensitivity of the biosensor is found to be about 1013. Besides showing an enhanced sensitivity compared with other FET- and TFET-based biosensors, the device proves itself convenient for low-power applications, thus opening up numerous directions for future research and applications.

Funder

Ministry of Science, Technological Development, and Innovations of the Republic of Serbia

Publisher

MDPI AG

Subject

Physical and Theoretical Chemistry,Analytical Chemistry

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