Therapeutic Potential of a Biodynamic Supplement on Skin Pressure Ulcers: A Randomized Clinical Study

Author:

Ferorelli Pasquale1,Doepp Manfred2,Lenzi Stefano3,Rovelli Roberto4,Gisonna Gennaro1,Maierà Giuseppe1,Antonelli Francesco5,Radaelli Massimo1,Shevchenko Anna6,Feriotto Giordana7,Mischiati Carlo8ORCID,Borromeo Ilaria9ORCID,Beninati Simone9ORCID

Affiliation:

1. Saint George Campus—Scuola di Formazione Certificata Nazionale e Internazionale, Via Oprandi 1, 24065 Lovere, Italy

2. Department Psychology and Sports Science, Giessen Justus, Liebig University Gießen, 35398 Gießen, Germany

3. Department of Health Engineering, Université Européenne de Bruxelles Jean Monnet, 1030 Brussels, Belgium

4. Department of Agricultural and Environmental Sciences, University of Milan, 20133 Milan, Italy

5. Scientific Association “A.R.S.S.—Associazione Ricerca Scientifica Sgurgola”, 00100 Rome, Italy

6. Department of Dermatology, Kabardine University, 121005 Nalchik, Russia

7. Department of Chemical, Pharmaceutical and Agricultural Sciences, University of Ferrara, 44121 Ferrara, Italy

8. Department of Neurosciences and Rehabilitation, University of Ferrara, 44121 Ferrara, Italy

9. Department of Biology, University of Rome Tor Vergata, Via della Ricerca Scientifica, 00100 Rome, Italy

Abstract

Pressure ulcers (PUs) are a debilitating and often painful condition. They are localized lesions on the skin and/or underlying tissues and are common in the elderly, people with mobility difficulties, diabetics, and vascular disease or malnutrition, as well as in those requiring intensive or palliative care. The prevention and treatment of PUs involve strategies to optimize hydration, circulation, and nutrition. Nutrition plays a key role in pressure ulcer care because wounds require macronutrients and micronutrients to heal. Reports relating to the effectiveness of “Complementary Enzyme Therapy” also in the vulnological field led us to this study, the aim of which was to test the activity of a biodynamic food supplement (Citozym®) rich in carbohydrates, vitamins, and amylase and lactase and characterized by marked antioxidant activity. Citozym® administered topically and/or systemically, and in particular in both administrations, in patients suffering from Pus, has shown a marked reduction in bedsores and, in many cases, complete healing. Furthermore, it was possible to observe a lower incidence of side effects compared to conventional therapies. The results obtained, confirmed by various tests and recognized by the scientific community, allow us to conclude that treatment with Citozym® could represent a new and effective strategy for the treatment of PUs.

Funder

A.R.S.S.

Publisher

MDPI AG

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