Line Illumination in Linear Array Photoacoustic Imaging Using a Powell Lens: A Proof-of-Concept Study

Author:

Ranjbaran Seyed Mohsen1ORCID,Kratkiewicz Karl2,Manwar Rayyan1ORCID,Avanaki Kamran134ORCID

Affiliation:

1. Richard and Loan Hill Department of Biomedical Engineering, University of Illinois at Chicago, Chicago, IL 60607, USA

2. Barbara Ann Karmanos Cancer Institute, Detroit, MI 48201, USA

3. Department of Dermatology, University of Illinois at Chicago, Chicago, IL 60607, USA

4. Section of Neonatology, Department of Pediatrics, UIHealth Children’s Hospital of the University of Illinois at Chicago, Chicago, IL 60612, USA

Abstract

Photoacoustic imaging (PAI) is a rapidly developing biomedical imaging technology. Linear array-based photoacoustic tomography (LA-PAT) is one of the most popular configurations of cross-sectional PAI due to its simplicity and clinical translatability. However, when using an optical fiber for LA-PAT, the optical beam shape is deformed due to rapid divergence and, therefore, a larger area on the tissue is illuminated (and the illumination across the linear array is non-uniform), leading to the acquisition of PA signals outside the desired cross-section, which generates artifacts and degrades image resolution. A Powell lens is an optical element that converts a circular beam profile to a nearly linear flat-top profile. In this paper, a Powell lens is used to generate a uniform line illumination scheme that is evaluated with Zemax OpticStudio 2023 R1.02. The system is then characterized experimentally, and the performance is compared with a conventional illumination scheme in LA-PAT.

Funder

National Institutes of Health

Publisher

MDPI AG

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