Moonlighting Proteins: Diverse Functions Found in Fungi

Author:

Curtis Nicole J.1,Patel Krupa J.1,Rizwan Amina2,Jeffery Constance J.1ORCID

Affiliation:

1. Department of Biological Sciences, University of Illinois at Chicago, Chicago, IL 60607, USA

2. Bay Path University, Longmeadow, MA 01106, USA

Abstract

Moonlighting proteins combine multiple functions in one polypeptide chain. An increasing number of moonlighting proteins are being found in diverse fungal taxa that vary in morphology, life cycle, and ecological niche. In this mini-review we discuss examples of moonlighting proteins in fungi that illustrate their roles in transcription and DNA metabolism, translation and RNA metabolism, protein folding, and regulation of protein function, and their interaction with other cell types and host proteins.

Funder

NSF

Publisher

MDPI AG

Subject

Plant Science,Ecology, Evolution, Behavior and Systematics,Microbiology (medical)

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