Is There an Association between Post-Traumatic Stress Disorder and the Incidence of Chronic Low Back Pain?

Author:

Kostev Karel12ORCID,Smith Lee3ORCID,Haro Josep Maria4,Konrad Marcel5ORCID,Koyanagi Ai4ORCID,Jacob Louis467ORCID

Affiliation:

1. Epidemiology, IQVIA, 60549 Frankfurt, Germany

2. University Clinic of Philipps University, 35037 Marburg, Germany

3. Centre for Health, Performance and Wellbeing, Anglia Ruskin University, Cambridge CB1 1PT, UK

4. Research and Development Unit, Parc Sanitari Sant Joan de Déu, CIBERSAM, ISCIII, Dr. Antoni Pujadas, 42, Sant Boi de Llobregat, 08830 Barcelona, Spain

5. Health & Social, FOM University of Applied Sciences for Economics and Management, 45127 Frankfurt am Main, Germany

6. Université Paris Cité, AP-HP, Lariboisière-Fernand Widal Hospital, Physical Medicine and Rehabilitation Department, 75010 Paris, France

7. Université Paris Cité, Inserm U1153, Epidemiology of Ageing and Neurodegenerative Diseases, 75010 Paris, France

Abstract

Background: Preliminary research suggests post-traumatic stress disorder (PTSD) is a risk factor for chronic low back pain (CLBP). However, this literature displays some limitations. Therefore, this study aimed to investigate the association between PTSD and the 10-year cumulative incidence of CLBP in adults from Germany. Methods: The present retrospective cohort study included adults diagnosed with PTSD in 1 of 1284 general practices in Germany in 2005–2020 (index date). Individuals without PTSD were matched to those with PTSD (1:1) using a propensity score based on age, sex, index year, duration of follow-up, and the mean number of consultations during follow-up. In patients without PTSD, the index date was a randomly selected visit date. Results: There were 60,664 patients included in the study. After adjusting for frequent comorbidities, there was a positive but non-significant association between PTSD and incident CLBP in the overall population (HR = 1.07, 95% CI = 0.99–1.15). Nonetheless, the relationship between PTSD and CLBP was statistically significant in the age group >60 years (HR = 1.24, 95% CI = 1.05–1.46). Conclusions: Conversely to previous research, PTSD was not associated with incident CLBP in this large German sample. Further longitudinal studies are warranted to corroborate these findings before drawing any firm conclusions.

Publisher

MDPI AG

Subject

General Medicine

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