Neat Chitosan Porous Materials: A Review of Preparation, Structure Characterization and Application

Abstract

This review presents an overview of methods for preparing chitosan-derived porous materials and discusses their potential applications. This family of materials has garnered significant attention owing to their biocompatibility, nontoxicity, antibacterial properties, and biodegradability, which make them advantageous in a wide range of applications. Although individual porous chitosan-based materials have been widely discussed in the literature, a summary of all available methods for preparing materials based on pure chitosan, along with their structural characterization and potential applications, has not yet been presented. This review discusses five strategies for fabricating porous chitosan materials, i.e., cryogelation, freeze-drying, sol-gel, phase inversion, and extraction of a porogen agent. Each approach is described in detail with examples related to the preparation of chitosan materials. The influence of the fabrication method on the structure of the obtained material is also highlighted herein. Finally, we discuss the potential applications of the considered materials.