New Genotypes of Coxiella burnetii Circulating in Brazil and Argentina

Author:

Mioni Mateus de Souza RibeiroORCID,Sidi-Boumedine Karim,Morales Dalanezi Felipe,Fernandes Joaquim Sâmea,Denadai Renan,Reis Teixeira Wanderson Sirley,Bahia Labruna Marcelo,Megid Jane

Abstract

Coxiella burnetii, the zoonotic agent of Q fever, has a worldwide distribution. Despite the vast information about the circulating genotypes in Europe and North America, there is a lack of data regarding C. burnetii strains in South America. Here, we show the presence of novel multispacer sequence typing (MST) genotypes of C. burnetii in two clusters detected in Brazil and Argentina that seem to be distant in parenthood. Argentinian strains isolated from a tick belongs to a new phylogenetic branch of C. burnetii, and the Brazilians strains may be related to MST 20 and 61. Multilocus variable number tandem repeats analysis (MLVA) typing provided a deeper resolution that may be related to host clusters of bovines, caprine, ovine, and ticks. Our results corroborate with the reports of geotypes of C. burnetii. Thus, we highlight the need for more genotyping studies to understand the genetic diversity of C. burnetii in South America and to confirm the hypothesis of host-related genotypes. We also emphasize the importance of virulence studies for a better understanding of Q fever in the region, which may help in surveillance and disease prevention programs.

Publisher

MDPI AG

Subject

Infectious Diseases,Microbiology (medical),General Immunology and Microbiology,Molecular Biology,Immunology and Allergy

Reference34 articles.

1. OIE Q Fever;Rousset,2018

2. Diagnosis and Management of Q Fever—United States, 2013: Recommendations from CDC and the Q Fever Working Group;Anderson;Morb. Mortal. Wkly. Rep.,2013

3. Coxiella;Marrie,2015

4. The Importance of Ticks in Q Fever Transmission: What Has (and Has Not) Been Demonstrated?

5. The Q fever epidemic in The Netherlands: history, onset, response and reflection

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