The Effect of Polyphenolics in Extracts from Natural Materials on Metabolic Activity of Metastatic Melanoma WM-266-4 Cells

Author:

Žitek Taja,Dariš Barbara,Finšgar MatjažORCID,Knez ŽeljkoORCID,Bjelić Dragana,Knez Hrnčič Maša

Abstract

The importance of natural crops in medicine and pharmacy is growing. Beside bioactive compounds used directly as therapeutic agents, there are also raw materials used for drug synthesis or as a basic model for new biologically active compounds. In this paper, the optimum conditions for material extraction of Curcuma longa, Lycium barbarum, Equisetum arvense, Vitis vinifera, and Rosmarinus officinalis were investigated to achieve high antioxidant levels. The main aim of this study was to verify the correlation between the content of antioxidants, proanthocyanidins and total phenolic substances for certain extracts from the raw materials (Curcuma longa, Lycium barbarum, Equisetum arvense, Vitis vinifera and Rosmarinus officinalis) and the reduction of the metabolic activity of skin cancer cells.

Publisher

MDPI AG

Subject

Fluid Flow and Transfer Processes,Computer Science Applications,Process Chemistry and Technology,General Engineering,Instrumentation,General Materials Science

Reference99 articles.

1. Cancer statistics, 2013

2. An overview of targeted cancer therapy

3. Drug-Resistance in Human Melanoma—Helmbach—2001—International Journal of Cancer—Wiley Online Libraryhttps://onlinelibrary.wiley.com/doi/full/10.1002/ijc.1378

4. The continuing search for antitumor agents from higher plants

5. Pure compound libraries; a new perspective for natural product based drug discovery

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3