Proton Therapy for Mandibula Plate Phantom

Author:

Senirkentli Güler BurcuORCID,Ekinci FatihORCID,Bostanci ErkanORCID,Güzel Mehmet SerdarORCID,Dağli ÖzlemORCID,Karim Ahmad M.ORCID,Mishra AlokORCID

Abstract

Purpose: In this study, the required dose rates for optimal treatment of tumoral tissues when using proton therapy in the treatment of defective tumours seen in mandibles has been calculated. We aimed to protect the surrounding soft and hard tissues from unnecessary radiation as well as to prevent complications of radiation. Bragg curves of therapeutic energized protons for two different mandible (molar and premolar) plate phantoms were computed and compared with similar calculations in the literature. The results were found to be within acceptable deviation values. Methods: In this study, mandibular tooth plate phantoms were modelled for the molar and premolar areas and then a Monte Carlo simulation was used to calculate the Bragg curve, lateral straggle/range and recoil values of protons remaining in the therapeutic energy ranges. The mass and atomic densities of all the jawbone layers were selected and the effect of layer type and thickness on the Bragg curve, lateral straggle/range and the recoil were investigated. As protons move through different layers of density, lateral straggle and increases in the range were observed. A range of energies was used for the treatment of tumours at different depths in the mandible phantom. Results: Simulations revealed that as the cortical bone thickness increased, Bragg peak position decreased between 0.47–3.3%. An increase in the number of layers results in a decrease in the Bragg peak position. Finally, as the proton energy increased, the amplitude of the second peak and its effect on Bragg peak position decreased. Conclusion: These findings should guide the selection of appropriate energy levels in the treatment of tumour structures without damaging surrounding tissues.

Publisher

MDPI AG

Subject

General Earth and Planetary Sciences,General Environmental Science

Reference46 articles.

1. Radiological Use of Fast Protons

2. Pituitary irradiation with highenergy proton beams: A pre-liminary report;Lawrence;Cancer Res.,1958

3. Evidence-Based Estimates of Outcome in Patients Irradiated for Intraocular Melanoma

4. Physics of proton interactions in matter;Gottschalk,2012

5. Monte Carlo and analytical calculation of proton pencil beams for computerized treatment plan optimization

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