Obesity as a Risk Factor for Severe COVID-19 in Hospitalized Patients: Epidemiology and Potential Mechanisms

Author:

Aburto Scarleth,Cisterna Mischka,Acuña Javiera,Ruíz Camila,Viscardi SharonORCID,Márquez José Luis,Villano InesORCID,Letelier Pablo,Guzmán NeftalíORCID

Abstract

SARS-CoV-2 infection is a global public health problem, causing significant morbidity and mortality. Evidence shows that obesity is a recognized risk factor for hospitalization, admission to critical care units, and the development of serious complications from COVID-19. This review analyzes the available epidemiological evidence that relates obesity to a higher risk of severity and mortality from COVID-19, examining the possible pathophysiological mechanisms that explain this phenomenon on a cellular and molecular level.

Funder

Vicerrectoría de Investigación y Postgrado, Universidad Católica de Temuco, Chile.

Publisher

MDPI AG

Subject

Health Information Management,Health Informatics,Health Policy,Leadership and Management

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