Antioxidant and Antidiabetic Activity of Algae

Author:

Abo-Shady Atef Mohamed1,Gheda Saly Farouk1,Ismail Gehan Ahmed1ORCID,Cotas João2ORCID,Pereira Leonel2ORCID,Abdel-Karim Omnia Hamdy13ORCID

Affiliation:

1. Botany Department, Faculty of Science, Tanta University, Tanta 31527, Egypt

2. MARE—Marine and Environmental Sciences Centre/ARNET—Aquatic Research Network, Department of Life Sciences, University of Coimbra, Calçada Martim de Freitas, 3000-456 Coimbra, Portugal

3. Bioprocess Engineering & AlgaePARC, Wageningen University and Research, 6700 AA Wageningen, The Netherlands

Abstract

Currently, algae arouse a growing interest in the pharmaceutical and cosmetic area due to the fact that they have a great diversity of bioactive compounds with the potential for pharmacological and nutraceutical applications. Due to lifestyle modifications brought on by rapid urbanization, diabetes mellitus, a metabolic illness, is the third largest cause of death globally. The hunt for an efficient natural-based antidiabetic therapy is crucial to battling diabetes and the associated consequences due to the unfavorable side effects of currently available antidiabetic medications. Finding the possible advantages of algae for the control of diabetes is crucial for the creation of natural drugs. Many of algae’s metabolic processes produce bioactive secondary metabolites, which give algae their diverse chemical and biological features. Numerous studies have demonstrated the antioxidant and antidiabetic benefits of algae, mostly by blocking carbohydrate hydrolyzing enzyme activity, such as α-amylase and α-glucosidase. Additionally, bioactive components from algae can lessen diabetic symptoms in vivo. Therefore, the current review concentrates on the role of various secondary bioactive substances found naturally in algae and their potential as antioxidants and antidiabetic materials, as well as the urgent need to apply these substances in the pharmaceutical industry.

Funder

Fundação para a Ciência e Tecnologia, I. P

European Regional Development Fund

Publisher

MDPI AG

Subject

Paleontology,Space and Planetary Science,General Biochemistry, Genetics and Molecular Biology,Ecology, Evolution, Behavior and Systematics

Reference170 articles.

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