Influence of a Constant Magnetic Field on the Mechanism of Adrenaline Oxidation

Abstract

In order to establish the role of the magnetic effect in the key stages of the autoxidation and initiated oxidation radical-chain reactions, the experimental data and kinetic analysis of the influence of a magnetic field on the oxidative transformations of adrenaline are presented in this work. In the case of autoxidation, the process is being controlled by the rate of adrenaline consumption in the gross process of quinoid oxidation. The analysis of the obtained results is estimative and is based on the assumption of the leading role of superoxide radical during the autoxidation. Superoxide radical concentration increases with the increase in the applied magnetic field strength, which leads to the decrease in the rate of initiation of the quinoid process. In the case of initiated oxidation, the results obtained are based on the known radical-chain mechanism, and they were interpreted using the theory of radical pairs. The observed magnetic effect is explained by the influence of a constant magnetic field on the mechanism of chain termination of radical-chain oxidation and/or initiation of the autoxidation process.