Essential Oils of Two Portuguese Endemic Species of Lavandula as a Source of Antifungal and Antibacterial Agents-Reference-Cited by-同舟云学术

Essential Oils of Two Portuguese Endemic Species of Lavandula as a Source of Antifungal and Antibacterial Agents

Published:2023-04-10 Issue:4 Volume:11 Page:1165
ISSN:2227-9717
Container-title:Processes
language:en
Short-container-title:Processes

Author:

Domingues Joana¹²^ORCID,Goulão Manuela³,Delgado Fernanda³⁴^ORCID,Gonçalves José Carlos³⁴^ORCID,Gonçalves Joana²,Pintado Cristina Santos³⁴⁵^ORCID

Affiliation:

1. Plant Biotechnology Centre of Beira Interior (CBPBI), 6001-909 Castelo Branco, Portugal

2. Health Sciences Research Centre (CICS), University of Beira Interior, 6200-506 Covilhã, Portugal

3. Polytechnic Institute of Castelo Branco-School of Agriculture (IPCB-ESA), 6001-909 Castelo Branco, Portugal

4. Research Centre for Natural Resources, Environment and Society, Polytechnic Institute of Castelo Branco (CERNAS-IPCB), 6001-909 Castelo Branco, Portugal

5. Research Unit of Life Quality in Rural Areas (QRural), Instituto Politécnico de Castelo Branco, 6601-909 Castelo Branco, Portugal

Abstract

Chemical investigations of L. stoechas subsp. luisieri and L. pedunculata essential oils were analyzed by GC-MS, and the antimicrobial activity was performed against bacteria and fungi isolated from food sources. The cytotoxicity of the essential oil was performed in NHDF cells using the MTT method. According to the results, the main compounds of L. stoechas subsp. luisieri essential oil were trans-α-necrodyl acetate (40.2%), lavandulyl acetate (11%), and trans-α-necrodol (10.4%), while fenchone (50.5%) and camphor (30.0%) in L. pedunculata essential oil. The antifungal activity of essential oils was confirmed with MIC values ranging from 1.2 to 18.7 µL/mL; for bacteria, it ranged from 4.7 to 149.3 µL/mL. Both the Lavandula species tested showed low or equal MIC and MBC/MFC values for L. stoechas subsp. luisieri essential oil, revealing greater efficacy in antimicrobial activity. The L. stoechas subsp. luisieri essential oil revealed cytotoxic effects (30 ± 2% of cell viability) in NHDF cells at all concentrations tested.

Funder

Research Center for Natural Resources, Environment and Society

Portuguese Funding Agency for Science Research and Technology

Programa Operacional EP-INTERREG V A Espanha-Portugal

Publisher

MDPI AG

Subject

Process Chemistry and Technology,Chemical Engineering (miscellaneous),Bioengineering

Link

https://www.mdpi.com/2227-9717/11/4/1165/pdf

Reference51 articles.

1. Upson, T.M., and Andrews, S. (2004). The Genus Lavandula.

2. Studies on Pharmaceutical Ethnobotany in Arrabida Natural Park (Portugal);Novais;J. Ethnopharmacol.,2004

3. Ethnopharmacological Notes about Ancient Uses of Medicinal Plants in Trás-Os-Montes (Northern of Portugal);Neves;J. Ethnopharmacol.,2009

4. Domingues, J., Delgado, F., Gonçalves, J.C., Zuzarte, M., and Duarte, A.P. (2023). Mediterranean Lavenders from Section Stoechas: An Undervalued Source of Secondary Metabolites with Pharmacological Potential. Metabolites, 13.

5. Lavandula luisieri Essential Oil as a Source of Antifungal Drugs;Zuzarte;Food Chem.,2012

Cited by 2 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. In Vitro Propagation and Conservation of Lavandula stoechas subsp. luisieri and Pterospartum tridentatum, Two Important Medicinal and Aromatic Species from Portugal;Plants;2024-08-01

2. Antibiofilm Effect of Lavandula multifida Essential Oil: A New Approach for Chronic Infections;Pharmaceutics;2023-08-15