Fuzzy Logic Control-Based HIFU System Integrated with Photoacoustic Imaging Module for Ex Vivo Artificial Tumor Treatment

Abstract

The objective of this study is to design a therapeutic method combining a portable high intensity focused ultrasound (HIFU) design which is suitable for the laboratory environment and a tailored integrated photo-acoustic imaging (PAI) system for monitoring thermal treatment. The electrical HIFU design is fabricated with changeable operating frequency and justified output power for resonating with different kinds of commercial transducers. The system’s control interface is built based on a touch screen to create a companionable interaction for users. The embedded fuzzy logic controller using the thermal input from the thermocouple sensor precisely drives the target temperature during HIFU exposure to achieve the expectedly coagulating results. The PAI system with 532-nm laser excitation is also integrated to define the affected region before and after HIFU treatment. The proposed fuzzy controller-integrated HIFU setup compatible with the PAI system is a feasible instrument in thermal therapy for ex vivo artificial tumors management.