Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS)-Reference-Cited by-同舟云学术

Wireless Device with Energy Management for Closed-Loop Deep Brain Stimulation (CLDBS)

Published:2023-07-14 Issue:14 Volume:12 Page:3082
ISSN:2079-9292
Container-title:Electronics
language:en
Short-container-title:Electronics

Author:

Matheus Nordi Tiago¹^ORCID,Augusto Ginja Gabriel¹,Gounella Rodrigo¹^ORCID,Talanoni Fonoff Erich²,Colombari Eduardo³,Moreira Melkzedekue M. Alcântara⁴,Afonso Jose A.⁵⁶^ORCID,Monteiro Vitor⁷^ORCID,Afonso Joao L.⁷^ORCID,Carmo João Paulo¹^ORCID

Affiliation:

1. Group of Metamaterials Microwaves and Optics (GMeta), Department of Electrical Engineering (SEL), University of São Paulo (USP), Avenida Trabalhador São-Carlense, Nr. 400, Parque Industrial Arnold Schimidt, São Carlos CEP 13566-590, SP, Brazil

2. Department of Neurology, Faculty of Medicine, Avenida Dr. Arnaldo, Nr. 455, Cerqueira César, São Paulo CEP 01246-903, SP, Brazil

3. Department of Physiology and Pathology, Faculty of Odontology, São Paulo State University (UNESP), Rua Humaitá, Nr. 1680, Araraquara CEP 14801-385, SP, Brazil

4. Department of Mechancial Engineering (SEM), University of São Paulo (USP), Avenida Trabalhador São-Carlense, Nr. 400, Parque Industrial Arnold Schimidt, São Carlos CEP 13566-590, SP, Brazil

5. CMEMS-UMinho, University of Minho, 4800-058 Guimarães, Portugal

6. LABBELS—Associate Laboratory, 4800-058 Guimarães, Portugal

7. ALGORITMI Research Centre/LASI, University of Minho, 4800-058 Guimarães, Portugal

Abstract

Deep brain stimulation (DBS) is an effective and safe medical treatment that improves the lives of patients with a wide range of neurological and psychiatric diseases, and has been consolidated as a first-line tool in the last two decades. Closed-loop deep brain stimulation (CLDBS) pushes this tool further by automatically adjusting the stimulation parameters to the brain response in real time. The main contribution of this paper is a low-size/power-controlled, compact and complete CLDBS system with two simultaneous acquisition channels, two simultaneous neurostimulation channels and wireless communication. Each channel has a low-noise amplifier (LNA) buffer in differential configuration to eliminate the DC signal component of the input. Energy management is efficiently done by the control and communication unit. The battery supports almost 9 h with both the acquisition and stimulation circuits active. If only the stimulation circuit is used as an Open Loop DBS, the battery can hold sufficient voltage for 24 h of operation. The whole system is low-cost and portable and therefore it could be used as a wearable device.

Funder

FAPESP agency

PQ scholarship

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Computer Networks and Communications,Hardware and Architecture,Signal Processing,Control and Systems Engineering

Link

https://www.mdpi.com/2079-9292/12/14/3082/pdf

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