Failure of a Multi-Centric Clinical Trial Investigating Neoadjuvant Radio-Chemotherapy in Resectable Pancreatic Carcinoma (NEOPA-NCT01900327)—Which Lessons Are Learnt?
Author:
Affiliation:
1. Department of General, Visceral and Thoracic Surgery, University-Hospital Hamburg-Eppendorf, Martinistrasse 52, 20246 Hamburg, Germany
2. Department of General and Visceral Surgery, HELIOS University Hospital Wuppertal, 42283 Wuppertal, Germany
Abstract
Funder
German Federal Ministry of Education and Research
Publisher
MDPI AG
Subject
Cancer Research,Oncology
Link
https://www.mdpi.com/2072-6694/15/17/4262/pdf
Reference38 articles.
1. Tachezy, M., Gebauer, F., Petersen, C., Arnold, D., Trepel, M., Wegscheider, K., Schafhausen, P., Bockhorn, M., Izbicki, J.R., and Yekebas, E. (2014). Sequential neoadjuvant chemoradiotherapy (CRT) followed by curative surgery vs. primary surgery alone for resectable, non-metastasized pancreatic adenocarcinoma: NEOPA—A randomized multicenter phase III study (NCT01900327, DRKS00003893, ISRCTN82191749). BMC Cancer, 14.
2. Prevalence, characteristics, and publication of discontinued randomized trials;Kasenda;JAMA,2014
3. A systematic review of discontinued trials suggested that most reasons for recruitment failure were preventable;Briel;J. Clin. Epidemiol.,2016
4. Barriers to participation in randomised controlled trials: A systematic review;Ross;J. Clin. Epidemiol,1999
5. A systematic review of resectability and survival after concurrent chemoradiation in primarily unresectable pancreatic cancer;Morganti;Ann. Surg. Oncol.,2010
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