Prevalence, Characteristics, and Publication of Discontinued Randomized Trials

Author:

Kasenda Benjamin1,von Elm Erik2,You John3,Blümle Anette4,Tomonaga Yuki5,Saccilotto Ramon1,Amstutz Alain1,Bengough Theresa2,Meerpohl Joerg J.4,Stegert Mihaela1,Tikkinen Kari A. O.6,Neumann Ignacio7,Carrasco-Labra Alonso8,Faulhaber Markus9,Mulla Sohail M.10,Mertz Dominik11,Akl Elie A.12,Bassler Dirk13,Busse Jason W.14,Ferreira-González Ignacio15,Lamontagne Francois16,Nordmann Alain1,Gloy Viktoria17,Raatz Heike1,Moja Lorenzo18,Rosenthal Rachel19,Ebrahim Shanil20,Schandelmaier Stefan21,Xin Sun22,Vandvik Per O.23,Johnston Bradley C.24,Walter Martin A.25,Burnand Bernard2,Schwenkglenks Matthias5,Hemkens Lars G.1,Bucher Heiner C.1,Guyatt Gordon H.10,Briel Matthias26

Affiliation:

1. Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland

2. Cochrane Switzerland, Institute of Social and Preventive Medicine (IUMSP), Lausanne University Hospital, Lausanne, Switzerland

3. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada14Department of Medicine, McMaster University, Hamilton, Ontario, Canada

4. German Cochrane Centre, Institute of Medical Biometry and Medical Informatics, Freiburg University Medical Center, Freiburg, Germany

5. Institute of Social and Preventive Medicine, University of Zurich, Zurich, Switzerland

6. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada15Department of Urology, Helsinki University Central Hospital, University of Helsinki, Helsinki, Finland

7. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada16Department of Internal Medicine, Pontificia Universidad Catolica de Chile, Santiago

8. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada25Evidence-Based Dentistry Unit, Faculty of Dentistry, Universidad de Chile, Santiago

9. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada17Department of Family Medicine, McMaster University, Hamilton, Ontario, Canada

10. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

11. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada26Michael G. DeGroote Institute for Infectious Diseases Research, McMaster University, Hamilton, Ontario, Canada

12. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada18Department of Internal Medicine, American University of Beirut, Beirut, Lebanon19Department of Medicine, State University of New York at Buffalo, Buffal

13. Center for Pediatric Clinical Studies, Department of Neonatology, University Children’s Hospital, Tuebingen, Germany

14. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada20Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada27Michael G. DeGroote Institute for Pain Research and Care, McMaster University,

15. Epidemiology Unit, Department of Cardiology, Vall d’Hebron Hospital and CIBER de Epidemiología y Salud Publica (CIBERESP), Barcelona, Spain

16. Centre de Recherche Clinique Étienne-Le Bel and Department of Medicine, Université de Sherbrooke, Sherbrooke, Canada

17. Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland13Institute of Nuclear Medicine, University Hospital Bern, Bern, Switzerland

18. IRCCS Orthopedic Institute Galeazzi, Milano, Italy

19. Department of Surgery, University Hospital Basel, Basel, Switzerland

20. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada20Department of Anesthesia, McMaster University, Hamilton, Ontario, Canada21Stanford Prevention Research Center, Stanford University, Stanford, California

21. Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland22Academy of Swiss Insurance Medicine, University Hospital of Basel, Basel, Switzerland

22. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada23Chinese Evidence-Based Medicine Center, West China Hospital, Sichuan University, Chengdu, China

23. Department of Medicine, Innlandet Hospital Trust-Division Gjøvik, Oppland, Norway

24. Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada12Department of Anesthesia and Pain Medicine, Hospital for Sick Children, Toronto, Ontario, Canada24Institute of Health Policy, Management and Evaluation,

25. Institute of Nuclear Medicine, University Hospital Bern, Bern, Switzerland

26. Basel Institute for Clinical Epidemiology and Biostatistics, University Hospital of Basel, Basel, Switzerland3Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada

Publisher

American Medical Association (AMA)

Subject

General Medicine

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