Electrochemical Assays for the Determination of Antidiabetic Drugs—A Review

Author:

Fendrych Katarzyna1ORCID,Górska-Ratusznik Anna2ORCID,Smajdor Joanna1ORCID

Affiliation:

1. Faculty of Materials Science and Ceramics, AGH University of Krakow, al. Mickiewicza 30, 30-059 Cracow, Poland

2. Lukasiewicz Research Network—Krakow Institute of Technology, 73 Zakopianska St., 30-418 Krakow, Poland

Abstract

This article presents the current state of knowledge regarding electrochemical methods for determining the active substances within drugs that are used in the treatment of type 1 and type 2 diabetes. Electrochemical methods of analysis, due to their sensitivity and easiness, are a great alternative to other, usually more expensive analytical assays. The determination of active substances mentioned in this review is based on oxidation or reduction processes on the surface of the working electrode. A wide variety of working electrodes, often modified with materials such as nanoparticles or conducting polymers, have been used for the highly sensitive analysis of antidiabetic drugs. The presented assays allow us to determine the compounds of interest in various samples, such as pharmaceutical products or different human bodily fluids.

Funder

Polish Ministry of Science and Education

Publisher

MDPI AG

Subject

Electrical and Electronic Engineering,Mechanical Engineering,Control and Systems Engineering

Reference138 articles.

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3. (2023, October 14). Global Burden of Disease Study 2019. Results. Institute for Health Metrics and Evaluation. Available online: https://vizhub.healthdata.org/gbd-results/.

4. Jean-Marie, E. (2018). Diagnosis and Classification of Diabetes Mellitus, Elsevier Inc.. [2nd ed.].

5. The Role of Incretins in Glucose Homeostasis and Diabetes Treatment;Kim;Pharmacol. Rev.,2008

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