Understanding Age-dependent Changes in Blood Pressure Regulation and Finding Novel Hypotensive Peptides in Aged Rats
Author:
Affiliation:
1. Graduate School of Agriculture, Kyoto University
Publisher
Brewing Society of Japan
Link
https://www.jstage.jst.go.jp/article/jbrewsocjapan/115/5/115_258/_pdf
Reference5 articles.
1. 1) 実験医学 2017年5月号 Vol.35 No.8臓器老化の本質に迫るステムセルエイジング
2. 2) Koyama D, Sun X, Sasai M, Matsumura S, Inoue K, Ohinata K. Ser-Tyr and Asn-Ala, vasorelaxing dipeptides found by comprehensive screening, reduce blood pressure via different age-dependent mechanisms. Aging (Albany NY) . 2019；11 (21): 9492-9499.
3. 3) Kagebayashi T, Kontani N, Yamada Y, Mizushige T, Arai T, Kino K, Ohinata K. Novel CCK-dependent vasorelaxing dipeptide, Arg-Phe, decreases blood pressure and food intake in rodents. Mol Nutr Food Res. 2012；56 (9): 1456-63.
4. 4) Kontani N, Omae R, Kagebayashi T, Kaneko K, Yamada Y, Mizushige T, Kanamoto R, Ohinata K. Characterization of Ile-His-Arg-Phe, a novel rice-derived vasorelaxing peptide with hypotensive and anorexigenic activities. Mol Nutr Food Res. 2014；58 (2): 359-64.
5. 5) Sasai M, Sun X, Okuda C, Nakato J, Kanamoto R, Ohinata K.Orally active anti-hypertensive peptides found based on enteroendocrine cell responses to a dipeptide library. Biochem Biophys Res Commun. 2018；503 (2): 1070-1074.
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