12-Lipoxygenase Products Reduce Insulin Secretion and β-Cell Viability in Human Islets
Author:
Affiliation:
1. Department of Internal Medicine (K.M., S.K.C., D.A.T.-F., J.L.N.), Eastern Virginia Medical School, Norfolk, Virginia 235207
2. Department of Medicine (C.S.N., R.W.), University of Virginia, Charlottesville, Virginia 22908
Publisher
The Endocrine Society
Subject
Biochemistry (medical),Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism
Link
http://academic.oup.com/jcem/article-pdf/95/2/887/9067959/jcem0887.pdf
Reference33 articles.
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2. The molecular biology of mammalian lipoxygenase and the quest for eicosanoid functions using lipoxygenase-deficient mice;Funk;Biochim Biophys Acta,1996
3. The role of 12-lipoxygenase in pancreatic-cells (review);Bleich;Int J Mol Med,1998
4. Nonobese diabetic (NOD) mice congenic for a targeted deletion of 12/15-lipoxygenase are protected from autoimmune diabetes;McDuffie;Diabetes,2008
5. Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice;Bleich;J Clin Invest,1999
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