A Thyroid-Specific Far-Upstream Enhancer in the Human Sodium/Iodide Symporter Gene Requires Pax-8 Binding and Cyclic Adenosine 3′,5′-Monophosphate Response Element-Like Sequence Binding Proteins for Full Activity and Is Differentially Regulated in Normal and Thyroid Cancer Cells

Author:

Taki Katsumi1,Kogai Takahiko1,Kanamoto Yoko1,Hershman Jerome M.1,Brent Gregory A.1

Affiliation:

1. Endocrinology Division, Veterans Affairs Greater Los Angeles Healthcare System and Department of Medicine, University of California-Los Angeles School of Medicine, Los Angeles, California 90073

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference66 articles.

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2. Increased expression of the Na+/I− symporter in cultured human thyroid cells exposed to thyrotropin and in Graves’ thyroid tissue.;Saito;J Clin Endocrinol Metab,1997

3. Regulation by thyroid-stimulating hormone of sodium/iodide symporter gene expression and protein levels in FRTL-5 cells.;Kogai;Endocrinology,1997

4. Medical therapy for differentiated thyroid carcinoma.;Dulgeroff;Endocr Rev,1994

5. Iodide symporter gene expression in human thyroid tumors.;Arturi;J Clin Endocrinol Metab,1998

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