Multiple Pituitary and Ovarian Defects in Krox-24 (NGFI-A, Egr-1)-Targeted Mice

Author:

Topilko Piotr1,Schneider-Maunoury Sylvie1,Levi Giovanni12,Trembleau Alain3,Gourdji Danièle4,Driancourt Marc-Antoine5,Rao Ch. V.6,Charnay Patrick1

Affiliation:

1. U-368, INSERM (P.T., S.S.-M., G.L., P.C.) Biologie Moléculaire du Développement Ecole Normale Supérieure 75230 Paris, France

2. Laboratory of Molecular Biology (G.L.) Advanced Biotechnology Center-IST Genova, Italy

3. URA CNRS 1414 (A.T.) Ecole Normale Supérieure 75230 Paris, France

4. U-159, INSERM (D.G.) Centre Paul Broca 75014 Paris, France

5. Institut National de la Recherche Agronomique Physiologie de la Reproduction des Mammifères Domestiques (M.-A.D.) 37380 Nouzilly, France

6. Laboratory of Molecular Reproductive Biology and Medicine Department of Obstetrics and Gynecology (C.V.R.) University of Louisville Health Science Center Louisville, Kentucky 40292

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference44 articles.

1. The hypothalamic-pituitary axis: co-development of two organs.;Treier;Curr Opin Cell Biol,1996

2. The Ames dwarf gene, df, is required early in pituirary ontogeny for the extinction of Rpx transcription and initiation of lineage-specific cell proliferation.;Gage;Mol Endocrinol,1996

3. The Pit-1 transcription factor gene is a candidate for the murine Snell dwarf mutation.;Camper;Genomics,1990

4. Dwarf locus mutants lacking three pituitary cell types result from mutations in the POU-domain gene pit-1.;Li;Nature,1990

5. GHRH receptor of little mice contains a missence mutation in the extracellular domain that disrupts receptor function.;Godfrey;Nat Genet,1993

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