GHRH receptor of little mice contains a missense mutation in the extracellular domain that disrupts receptor function
Author:
Publisher
Springer Science and Business Media LLC
Subject
Genetics
Link
http://www.nature.com/articles/ng0793-227.pdf
Reference56 articles.
1. Eicher, E.M. & Beamer, W.G. Inherited ateliotic dwarfism in mice: characterization of the mutation, little, on chromosome 6. J. Hered. 67, 87–91 (1976).
2. Beamer, W.G. & Eicher, E.M. Stimulation of growth in the little mouse. J. Endocrinol. 71, 37–45 (1976).
3. Hammer, R.E., Palmiter, R.D. & Brinster, R.L. Partial correction of murine hereditary growth disorder by germ-line incorporation of a new gene. Nature 311, 65–67 (1984).
4. Jansson, J.-O., Downs, T.R., Beamer, W.G. & Frohman, L.A. Receptor-associated resistance to growth hormone-releasing factor in dwarf “little” mice. Science 232, 511–512 (1986).
5. Guillemin, R. et al. Growth hormone-releasing factor from a human pancreatic tumor that caused acromegaly. Science 218, 585–587 (1982).
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