Hepatic Insulin Gene Expression as Treatment for Type 1 Diabetes Mellitus in Rats
Author:
Affiliation:
1. Department of Cell Biology (P.M., R.C.E., S.L.C.W.) ,Houston Texas 77030
2. Department of Pediatrics (K.C.C.), Houston Texas 77030
3. Howard Hughes Medical Institute (S.L.C.W.), Baylor College of Medicine, Houston Texas 77030
Publisher
The Endocrine Society
Subject
Endocrinology,Molecular Biology,General Medicine
Link
http://academic.oup.com/mend/article-pdf/11/6/833/8956300/mend0833.pdf
Reference11 articles.
1. The physiology of insulin in man.;Cahill;Diabetes,1971
2. Coma and diabetes.;Vignati;Joslin’s Diabetes Mellitus.,1985
3. Gene therapy for diabetes mellitus in rats by hepatic expression of insulin.;Kolodka;Proc Natl Acad Sci USA,1995
4. Regulated expression of human insulin in the liver of transgenic mice corrects diabetic alterations.;Valera;FASEB J,1994
5. Insulin exerts metabolic and growth-promoting effects by a direct action on the liver in vivo: clarification of the functional significance of the portal vascular link between the beta cells of the pancreatic islets and the liver.;Griffen;Proc Natl Acad Sci USA,1987
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