mRNA destabilization improves glycemic responsiveness of transcriptionally regulated hepatic insulin gene therapyin vitroandin vivo-Reference-Cited by-同舟云学术

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mRNA destabilization improves glycemic responsiveness of transcriptionally regulated hepatic insulin gene therapyin vitroandin vivo

Published:2017-03 Issue:3 Volume:19 Page:e2946
ISSN:1099-498X
Container-title:The Journal of Gene Medicine
language:en
Short-container-title:J Gene Med

Author:

Thulé Peter M.¹²,Lin Yulin¹,Jia Dingwu¹,Olson Darin E.¹,Tang Shiue-Cheng²³⁴,Sambanis Athanassios²³⁵

Affiliation:

1. Atlanta VA Medical Center, Division of Endocrinology, Diabetes, & Lipids; Emory University School of Medicine; Decatur Georgia USA

2. Parker H. Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology; Atlanta Georgia USA

3. School of Chemical & Biomolecular Engineering; Georgia Institute of Technology; Atlanta Georgia USA

4. Department of Medical Science; National Tsing Hua University; Taiwan USA

5. Department of Biomedical Engineering; Georgia Institute of Technology; Atlanta Georgia USA

Publisher

Wiley

Subject

Genetics (clinical),Drug Discovery,Genetics,Molecular Biology,Molecular Medicine

Reference34 articles.

1. Gene therapy for diabetes mellitus in rats by hepatic expression of insulin;Kolodka;Proc Natl Acad Sci U S A,1995

2. Hepatic insulin expression improves glycemic control in type 1 diabetic rats;Dong;Diabetes Res Clin Pract,2001

3. Hepatic insulin gene expression as treatment for type 1 diabetes mellitus in rats;Muzzin;Mol Endocrinol,1997

4. Glucose responsive hepatic insulin gene therapy of spontaneously diabetic BB/Wor rats;Olson;Hum Gene Ther,2003

5. Regulated hepatic insulin gene therapy of STZ-diabetic rats;Thule;Gene Ther,2000

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