Potential Clinical Error Arising From Use of HbA1c in Diabetes: Effects of the Glycation Gap

Author:

Nayak Ananth U1,Singh Baldev M23,Dunmore Simon J2ORCID

Affiliation:

1. Department of Endocrinology and Diabetes, University Hospital of North Midlands NHS Trust, Stoke on Trent, United Kingdom

2. Diabetes Research Group, School of Medicine and Clinical Practice, University of Wolverhampton, Wolverhampton, United Kingdom

3. Wolverhampton Diabetes Centre, New Cross Hospital, Royal Wolverhampton NHS Trust, Wolverhampton, United Kingdom

Funder

Wolverhampton Diabetes Trust

Rotha Abraham Trust

Publisher

The Endocrine Society

Subject

Endocrinology,Endocrinology, Diabetes and Metabolism

Reference73 articles.

1. World Health Organization. Use of glycated haemoglobin (HbA1c) in the diagnosis of diabetes mellitus. Available at: www.who.int/diabetes/publications/report-hba1c_2011.pdf. Accessed 7 March 2018.

2. When HbA1c and blood glucose do not match: how much is determined by race, by genetics, by differences in mean red blood cell age;Cohen;J Clin Endocrinol Metab.,2019

3. Clinical impact of variability in HbA1c as assessed by simultaneously measuring fructosamine and use of error grid analysis;Macdonald;Ann Clin Biochem,2008

4. Evidence for consistency of the glycation gap in diabetes;Nayak;Diabetes Care,2011

5. Discordance between HbA1c and fructosamine: evidence for a glycosylation gap and its relation to diabetic nephropathy;Cohen;Diabetes Care,2003

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