A proteolytic fragment of insulin-like growth factor (IGF) binding protein-3 that fails to bind IGFs inhibits the mitogenic effects of IGF-I and insulin.
Author:
Publisher
The Endocrine Society
Subject
Endocrinology
Link
http://academic.oup.com/endo/article-pdf/137/8/3206/10639924/endo3206.pdf
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1. Normal and Aberrant Growth in Children;Williams Textbook of Endocrinology;2016
2. Paracrine Factors of Human Fetal MSCs Inhibit Liver Cancer Growth Through Reduced Activation of IGF-1R/PI3K/Akt Signaling;Molecular Therapy;2015-04
3. IGFBP7 Binds to the IGF-1 Receptor and Blocks Its Activation by Insulin-Like Growth Factors;Science Signaling;2012-12-18
4. Human IGF Binding Protein-3 Overexpression Impairs Glucose Regulation in Mice via an Inhibition of Insulin Secretion;Endocrinology;2011-03-29
5. Normal and Aberrant Growth;Williams Textbook of Endocrinology;2011
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