An Ensemble Model of the Male Gonadal Axis: Illustrative Application in Aging Men

Author:

Keenan Daniel M.1,Takahashi Paul Y.2,Liu Peter Y.3,Roebuck Pamela D.3,Nehra Ajay X.4,Iranmanesh Ali5,Veldhuis Johannes D.3

Affiliation:

1. Department of Statistics, University of Virginia (D.M.K.), Charlottesville, Virginia 22903

2. Primary Care Internal Medicine, Department of Internal Medicine (P.Y.T.), Mayo School of Graduate Medical Education, General Clinical Research Center, Mayo Clinic, Rochester, Minnesota 55905

3. Endocrine Research Unit (P.Y.L., P.D.R., J.D.V.), Mayo School of Graduate Medical Education, General Clinical Research Center, Mayo Clinic, Rochester, Minnesota 55905

4. Department of Urology (A.X.N.), Mayo School of Graduate Medical Education, General Clinical Research Center, Mayo Clinic, Rochester, Minnesota 55905

5. Endocrine Service, Medical Section, Salem Veterans Affairs Medical Center (A.I.), Salem, Virginia 24153

Publisher

The Endocrine Society

Subject

Endocrinology

Reference59 articles.

1. The rationale, efficacy and safety of androgen therapy in older men: future research and current practice recommendations.;Liu;J Clin Endocrinol Metab,2004

2. Measures of bioavailable serum testosterone and estradiol and their relationships with muscle strength, bone density, and body composition in elderly men.;Beld;J Clin Endocrinol Metab,2000

3. An ensemble perspective of aging-related hypoandrogenemia in men.;Veldhuis,2004

4. Aging results in attenuated gonadotropin releasing hormone-luteinizing hormone axis responsiveness to glutamate receptor agonist N-methyl-d-aspartate.;Bonavera;J Neuroendocrinol,1998

5. Luteinizing hormone and testosterone secretion in young and old male mice;Coquelin;Am J Physiol,1982

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