Newborn Screening for Primary Congenital Hypothyroidism: Estimating Test Performance at Different TSH Thresholds

Author:

Knowles Rachel L1,Oerton Juliet1,Cheetham Timothy2,Butler Gary3,Cavanagh Christine4,Tetlow Lesley5,Dezateux Carol6

Affiliation:

1. Life Course Epidemiology and Biostatistics, UCL Great Ormond Street Institute of Child Health, London, United Kingdom

2. Newcastle University and Department of Paediatric Endocrinology, Royal Victoria Infirmary, Newcastle-upon-Tyne, United Kingdom

3. Paediatric and Adolescent Endocrinology, University College London Hospitals NHS Foundation Trust and UCL Great Ormond Street Institute of Child Health, London, United Kingdom

4. National Newborn Blood Spot Screening Programme, Public Health England, London, United Kingdom

5. Department of Clinical Biochemistry, Manchester University NHS Foundation Trust, Manchester, United Kingdom

6. Centre for Primary Care and Public Health, Barts and the London School of Medicine and Dentistry, Queen Mary University London, United Kingdom

Funder

Public Health England

Publisher

The Endocrine Society

Subject

Biochemistry, medical,Clinical Biochemistry,Endocrinology,Biochemistry,Endocrinology, Diabetes and Metabolism

Reference33 articles.

1. Evidence or enthusiasm? Why yields from UK newborn screening programmes for congenital hypothyroidism are increasing;Pollitt;Arch Dis Child,2016

2. European Society for Paediatric Endocrinology consensus guidelines on screening, diagnosis, and management of congenital hypothyroidism;Léger;J Clin Endocrinol Metab,2014

3. Newborn blood spot screening: programme overview. 2013. Available at: www.gov.uk/guidance/newborn-blood-spot-screening-programme-overview. Accessed 25 July 2017.

4. Defining the newborn blood spot screening reference interval for TSH: impact of ethnicity;Peters;J Clin Endocrinol Metab,2016

5. Iodine status of UK schoolgirls: a cross-sectional survey;Vanderpump;Lancet,2011

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