Estrogen Receptor α Interacts with Gα13 to Drive Actin Remodeling and Endothelial Cell Migration via the RhoA/Rho Kinase/Moesin Pathway

Author:

Simoncini Tommaso1,Scorticati Camila1,Mannella Paolo1,Fadiel Ahmed2,Giretti Maria S.1,Fu Xiao-Dong1,Baldacci Chiara1,Garibaldi Silvia1,Caruso Antonella1,Fornari Letizia1,Naftolin Frederick3,Genazzani Andrea R.1

Affiliation:

1. Molecular and Cellular Gynecological Endocrinology Laboratory (T.S., C.S., P.M., M.S.G., X.-D.F., C.B., S.G., A.C., L.F., A.R.G.), Department of Reproductive Medicine and Child Development, University of Pisa, 56100 Pisa, Italy;

2. Department of Obstetrics, Gynecology and Reproductive Sciences (A.F.), Yale University, New Haven, Connecticut 06520

3. Department of Obstetrics and Gynecology (F.N.), New York University, New York, New York 10010;

Publisher

The Endocrine Society

Subject

Endocrinology,Molecular Biology,General Medicine

Reference41 articles.

1. Estrogen receptors, estradiol, and diethylstilbestrol in early development: the mouse as a model for the study of estrogen receptors and estrogen sensitivity in embryonic development of male and female reproductive tracts.;Greco;Endocr Rev,1993

2. Estradiol-induced ezrin overexpression in ovarian cancer: a new signaling domain for estrogen.;Song;Cancer Lett,2005

3. The protective effects of estrogen on the cardiovascular system.;Mendelsohn;N Engl J Med,1999

4. Non-genomic actions of sex steroid hormones.;Simoncini;Eur J Endocrinol,2003

5. Aromatase and estrogen receptor immunoreactivity in the coronary arteries of monkeys and human subjects.;Diano;Menopause,1999

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