Affiliation:
1. Lietuvos sveikatos mokslų universiteto Medicinos akademijos Anesteziologijos klinika
2. Lietuvos sveikatos mokslų universiteto Medicinos akademija
Abstract
In these latter decades neurotoxicity of general anaesthetics has been demonstrated in neonatal animal models. These data raised a concern about the safety of neonatal and paediatric anaesthesia. However, prospective epidemiological studies in humans are still ongoing. Biological markers, which could be associated with anaesthesia and outcome would be helpful in timely decisions regarding clinical practice in newborns and infants. To date, some brain specific proteins have been studies in various brain damage scenarios in neonates, children and adults. The purpose of the present paper is to describe current knowledge, based on experimental and clinical data, on the influence of anaesthetics on the developing brain and the applicability of certain biomarkers in cases of cerebral cell damage.
Publisher
Association of Lithuanian Serials (Publications)
Reference42 articles.
1. Brain specific proteins in serum: do they reliably reflect brain damage?;Vos, P. E.;Shock,2002
2. Kinetics of serum S100β in newborns with intracranial lesions;Murabayashi, M.;Pediatrics International,2008
3. Perinatal asphyxia: Kidney failure does not affect S100β urine concentrations;Risso, F. M.;Clinica Chimica Acta,2012
4. S100β protein in serum as a prognostic marker for cerebral injury in term newborn infants with hypoxic ischemic encephalopathy;Thorngren-Jerneck, K.;Pediatric Research,2004
5. S100β protein family and its application in clinical practice;Sedaghat, F.;Hippokratia,2008
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