The “Values in Action” (VIA) framework is currently the most prominent approach to conceptualizing human character. VIA posits 24 character strengths that are purportedly valued across cultures and promote the well-being of both individuals and communities. However, unresolved limitations in the assessment of these character strengths continue to hamper theoretical progress in research on human character based on the VIA framework. Here we sought to lay a new foundation for ad-vanced assessment of strengths by refining and extensively validating an existing open-science inventory from the International Personality Item Pool (IPIP). Using data from a U.S. community sample and four quota samples from the United Kingdom and Germany, we investigated whether valid, cross-culturally comparable, and economical assessment of the VIA character strengths is possible with the IPIP. Experts selected suitable items with the aim to obtain 24 balanced-keyed short scales. Different experts then translated these items to German. Through exploratory and confirmatory factor analysis, we established essential unidimensionality and well-fitting measure-ment models for each scale. All scales achieved at least partial scalar invariance across languages. Reliability estimates were satisfactory. Extensive analyses of the strengths’ nomological network placed character strengths between Big Five personality traits and basic human values, confirming that VIA strengths emphasize self-transcendence rather than self-enhancement. With few excep-tions, the 24 character strengths scales were sufficiently distinct from the Big Five, and many showed incremental predictive validity, also for “good life” criteria. The 96-item inventory “IPIP-VIA-R” offers a sound and fully open-science approach to future research on character strengths.